Sunosi (solriamfetol) and Modafinil are both FDA-approved medications used to treat excessive daytime sleepiness (EDS) associated with narcolepsy and obstructive sleep apnea (OSA). While they share a goal—to improve wakefulness—their mechanisms of action, clinical effectiveness, side effect profiles, and cost structures differ in ways that may influence treatment decisions. Key Takeaways What Is Sunosi (Solriamfetol)?…

Restless Leg Syndrome (RLS) is marked by an uncontrollable urge to move the legs, often triggered by uncomfortable sensations that occur during the evening or nighttime while sitting or lying down. Modafinil, primarily used to treat narcolepsy, has been investigated for its potential to relieve RLS symptoms. Insights from a patent on modafinil’s use for…

Modafinil, initially prescribed for narcolepsy and other sleep disorders, has gained popularity as a cognitive enhancer. Its effects on dopamine levels are particularly significant, as dopamine is key to cognitive function and motivation. Exploring how Modafinil influences dopamine provides insight into its impact on cognitive performance and mental clarity. Modafinil and Its Uses Medical Uses…

Modafinil, widely recognized for its wakefulness-promoting effects, was originally developed to treat conditions such as narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It has since gained popularity for off-label uses like cognitive enhancement and improved focus, particularly among students and professionals. However, its rising use has raised concerns about potential health risks, including…

What is Modafinil? Modafinil (brand name Provigil®) is a prescription medication primarily used to promote wakefulness in individuals with sleep disorders, such as narcolepsy, shift work sleep disorder, and obstructive sleep apnea (FDA, 2007).Beyond its approved uses, modafinil has seen growing off-label adoption as a cognitive enhancer among healthy individuals (Kumar, 2008; Porsdam-Mann & Sahakian,…

Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME), is a long-term condition characterized by persistent fatigue that is not relieved by rest. Standard therapies such as cognitive behavioral therapy (CBT) and graded exercise therapy (GET) have limited effectiveness for many patients. Modafinil, a medication approved to treat excessive daytime sleepiness in narcolepsy, is increasingly considered…

Both Modafinil and Methylphenidate are used to treat conditions characterized by excessive daytime sleepiness and attention difficulties — but which is right for you? What Are Modafinil and Methylphenidate? Modafinil Modafinil (Provigil) is a wakefulness-promoting agent primarily prescribed for narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD). Though the exact mechanism isn’t…

Interest in nootropics and psychedelics has surged, particularly for their potential to enhance cognitive function and creativity. Modafinil, a prescription drug known for treating sleep disorders and boosting alertness, and psilocybin, the active compound in magic mushrooms known for altering perception and addressing mental health challenges, have drawn significant attention. Exploring their combined effects reveals…